Cysts ^ Jump up to: a b Samarasekera EJ, Sawyer L, Wonderling D, Tucker R, Smith CH (2013). "Topical therapies for the treatment of plaque psoriasis: systematic review and network meta-analyses". Br J Dermatol. 168 (5): 954–67. doi:10.1111/bjd.12276. PMID 23413913.
^ Jump up to: a b c d e f g h i j k l m n o p q Boehncke, WH; Schön, MP (26 May 2015). "Psoriasis". Lancet. 386: 983–94. doi:10.1016/S0140-6736(14)61909-7. PMID 26025581.
Psoriasis: What’s the Genetic Link? Tar soaps and shampoos Webcasts The primary cause of psoriasis remains unknown. Abnormal epidermal cell kinetics and abnormal activation of immune mechanisms are thought to be the major contributors, and treatment may affect one or both of these mechanisms.4 Psoriasis is characterized by red, scaling plaques, ranging from only a few lesions to total involvement of the skin. The primary lesion is a well-demarcated erythematous plaque with a silvery scale. Characteristically, psoriasis is symmetrically distributed, with lesions frequently located on the ears, elbows, knees, umbilicus, gluteal cleft and genitalia (Figure 1). The joints (psoriatic arthritis), nails and scalp may also be affected.
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Psoriasis Statistics Shampoo More severe psoriasis may require phototherapy with ultraviolet A (UVA) or B (UVB) light, which requires coming two to three times a week for treatment. Severe psoriasis not responding to the above may need tablets such as methotrexate, acitretin and cyclosporin. Unfortunately, oral medications can cause side effects such as bone marrow damage, liver damage and kidney damage, and requires regular blood tests to detect these side effects. New injectable biologic agents which are safe and effective are also available for patients who do not respond to conventional therapy.
Psoriasis is a condition which tends to run in families. Several different genes have been identified but the exact way in which the disorder moves from generation to generation has not yet been established. What is known is that both the immune system and genetics are important in its development. So although the potential to develop psoriasis is genetically inherited, it is by no means certain that it will ever occur.
Systemic medication Scopus (177) Slideshow Tips to Help You Stop Wasting Time These agents are potent drugs given by mouth or injection. They block inflammation and have effects on the immune system. The effect on skin is probably secondary to the effect on white blood cells.
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Hide People with HIV are more likely to develop psoriasis than people with healthy immune systems.
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