Dendritic cells bridge the innate immune system and adaptive immune system. They are increased in psoriatic lesions and induce the proliferation of T cells and type 1 helper T cells (Th1). Targeted immunotherapy as well as psoralen and ultraviolet A (PUVA) therapy can reduce the number of dendritic cells and favors a Th2 cell cytokine secretion pattern over a Th1/Th17 cell cytokine profile. Psoriatic T cells move from the dermis into the epidermis and secrete interferon-γ and interleukin-17. Interleukin-23 is known to induce the production of interleukin-17 and interleukin-22. Interleukin-22 works in combination with interleukin-17 to induce keratinocytes to secrete neutrophil-attracting cytokines.
Psoriasis, Easy-to-Read Fast Facts Journal of Genetic Disorders & Genetic Reports Hybrid Open Access Journal
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Though the data isn’t complete, research suggests cases of psoriasis are becoming more common. Whether that’s because people are developing the skin condition or doctors are just getting better at diagnosing it is unclear.
Journal of Traditional Medicine & Clinical Naturopathy Open Access Journal
Reviewed by Stephanie S. Gardner, MD on October 30, 2017 May affect up to 55 per cent of patients with psoriasis Psoriasis.: 295-331 WB Saunders, Philadelphia; 1996
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USA.gov Severity Publication Signup Blog authors Psoriasis is a common, chronic, immune-mediated skin disease with characteristic red, scaly plaques caused by the excessive proliferation of skin cells.
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What Is Ulcerative Colitis? Occurs in less than 2 per cent of psoriasis cases Eye Disorders Capon F 2.4 Microbes Guttate. This affects people younger than 30 and is usually triggered by a bacterial infection such as strep throat. It's marked by small sores on the trunk, arms, legs and scalp.
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